The Hertie Stiftung (Hertie Foundation), headquartered at Grüneburgweg 105 in Frankfurt am Main, is one of Germany’s largest private foundations, managing assets of roughly 1.2 billion euros and allocating an annual endowment of 25 to 30 million euros. Founded in 1974 by Hans-Georg Karg and Brigitte Gräfin von Norman, the foundation's origins trace to the legacy of the Tietz family’s department stores. In the 1930s, these stores were forcibly transferred ("aryanized") during the Nazi era; Georg Karg subsequently became owner after the dispossession of the founding Jewish family.

The Hertie Foundation's historical legacy has, in recent years, drawn scrutiny and initiated public debate, especially regarding transparent engagement with its past. A commissioned independent study and further historical research have been conducted to address these concerns.

The foundation’s scope centers on two key areas: brain research and democracy strengthening. Since its inception, Hertie Stiftung has put over 450 million euros toward its projects and grants in neuroscience, education, and societal integration. Notable current projects include the Hertie School in Berlin—a university focused on governance and public policy with over 500 students—and the Hertie Institute for Clinical Brain Research in Tübingen. The foundation has also funded the reconstruction of prominent cultural sites in Frankfurt, such as the Städel Museum and the city library, and supported initiatives for young people with migration backgrounds through the START Foundation.

While its focus is Germany-wide, many pilot projects begin in Frankfurt before extending further. The foundation maintains an active presence in Berlin to foster political and societal impact.